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ea0032oc2.6 | Bone & Calcium | ECE2013

Hypomineralized teeth as biomarkers of exposure to endocrine disruptors

Jedeon Katia , Molla De La Dure Muriel , Brookes Steven , Marciano Clemence , Canivenc-Lavier Marie-Chantal , Berdal Ariane , Babajko Sylvie

MIH for Molar Incisor Hypomineralization is a recently described pathology affecting around 18% of six year old children. Although a number of putative factors have been hypothesized, etiology of MIH remains unknown. The parallel increase of exposure to endocrine disruptors (EDs) and the prevalence of MIH led us to investigate a possible relationship between both events.Rats were orally exposed daily to low dose of bisphenol A (BPA), genistein, vinclozol...